Dedicated to extinguishing the fear and burden of serious disease by advancing real-world care.

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What real-world care means to us

To achieve more precise care for every patient, we need to transform real-world evidence into insights that can directly impact care. At Syapse, that is Real-world care.

It’s found in the way we empower healthcare organizations to work together in active, transparent partnerships, delivering complete patient insights to answer the questions that matter and then purposefully applying it at where patients receive care – driving real impact for cancer patients and beyond.

Data Intelligence

It is the foundation of every engagement. We bring together structured and unstructured real-world data, AI and deep knowledge to generate the kind of meaningful real-world evidence that saves lives.

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It is the foundation of every engagement. We bring together structured and unstructured real-world data, AI and deep knowledge to generate the kind of meaningful real-world evidence that saves lives.

Insight Analytics

We deliver meaningful insights by combining curated patient cohorts, addressable questions through varied delivery types (e.g., customized reports, sandbox, explorer) to get you the answers you need, in the format best suited for you and your team.

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We deliver meaningful insights by combining curated patient cohorts, addressable questions through varied delivery types (e.g., customized reports, sandbox, explorer) to get you the answers you need, in the format best suited for you and your team.

Applied Experience

Strategic collaborations between life sciences companies, molecular labs, and regulators in the Learning Health Network facilitated by Syapse’s deep partnerships with health systems. Using a proprietary approach, we address gaps in care and monitor outcomes.

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Strategic collaborations between life sciences companies, molecular labs, and regulators in the Learning Health Network facilitated by Syapse’s deep partnerships with health systems. Using a proprietary approach, we address gaps in care and monitor outcomes.

How we are able to deliver on our promise


Expert Team

Our determined clinical, business, and technology experts bring the support and knowledge required to advance real-world care.


The Syapse Learning Health Network

This international network is powered by healthcare providers, life-science companies, molecular labs, and regulators, aspiring to transform real-world evidence and insights into a better patient experience you can actually see.


Advanced Technologies

Our proprietary real-world data platform brings together rich data from a multitude of data sources and harmonizes them while maintaining provenance through the system. It leverages AI and NLP to accelerate the capture of typically unstructured data elements while verifying reliability of the outputs versus a source of truth.

The Latest News

04/21/2022

Using NLP Technology To Uncover Real-World Patient Insights

By Tiffany Druley

It’s estimated that humans create a combined 2.5 quintillion bytes of data each day – and that around 90% of all data to ever exist was created in just the last few years.

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01/13/2022

Dr. Ali on the Need to Understand Real-World Disparities in BRCA Testing in TNBC

By Tiffany Druley

During the 2021 San Antonio Breast Cancer Symposium, findings from a real-world analysis evaluating racial disparities in BRCA testing for patients with TNBC were presented in a virtual poster. The results showed that the rate of BRCA testing was high overall in evaluated patients with TNBC, although a larger proportion of White patients received testing compared with Black or African American patients.

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01/10/2022

Achieving Comprehensive Patient Care Using Natural Language Processing

By Tiffany Druley

Telehealth has seen unprecedented growth within the past few years. As a result of this adoption, at the onset of the COVID-19 pandemic, health care organizations were quickly able to adapt their processes from being rooted in in-person care to relying on virtual care.

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01/05/2022

Illumina, Syapse Partner on Study of Comprehensive Genomic Profiling in Advanced Cancer

By Tiffany Druley

Syapse said on Tuesday that it has partnered with Illumina to assess uptake and…

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01/05/2022

Illumina and Syapse Partner on Biomarker Testing Research Across Oncology Practices

By Tiffany Druley

Syapse, a real-world evidence company that informs cancer care, announced a partnership with Illumina aimed at assessing the real-world uptake and actionability of comprehensive genomic profiling in the community oncology health system setting.

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01/04/2022

Illumina, Syapse Partner on Study of Comprehensive Genomic Profiling in Advanced Cancer

By Tiffany Druley

Syapse said on Tuesday that it has partnered with Illumina to assess uptake and actionability of comprehensive genomic profiling in the community oncology health system setting.

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01/04/2022

Illumina and Syapse Partner on Biomarker Testing Research Across Oncology Practices

By Tiffany Druley

Syapse, a leading real-world evidence company dedicated to extinguishing the fear and burden of serious diseases by advancing real-world care, today announced a partnership with Illumina, aimed at assessing the real-world uptake and actionability of comprehensive genomic profiling in the community oncology health system setting.

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12/12/2021

SABCS 2021 Sheds Light on Inequities Affecting Black Patients

By Tiffany Druley

Women who are Black or African American often have worse breast cancer outcomes and greater risk of death from breast cancer than white women.

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12/10/2021

Real-World Data Points to Racial Disparity in BRCA1/2 Testing Among TNBC Patients

By Tiffany Druley

An evaluation of real-world BRCA1/2 testing patterns among triple-negative breast cancer patients has shown that African American women within four community health systems in Syapse’s Learning Health Network are facing more barriers in accessing testing.

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12/10/2021

Real-World Data Points to Racial Disparity in BRCA1/2 Testing Among TNBC Patients

By Tiffany Druley

An evaluation of real-world BRCA1/2 testing patterns among triple-negative…

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11/08/2021

You Don’t Need a Big Funding Round to Invest in DEI

By Tiffany Druley

Senior Vice President of People Michelle Kemling said rather than spending some of that money on a one-time event or training, an employee-led DEI committee continuously asks how they can make Syapse a better place to work. Executives prioritize DEI at the company and their support empowers employees to take grassroots action in building internal initiatives and treating DEI like a part of their core roles, Kemling said.

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10/15/2021

The 25 small and midsize companies that offer the best perks and benefits

By Chris Burkhardt

Comparably just released its latest ranking: the Best Companies for Perks and Benefits.

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10/11/2021

Taking the Call: Multisource Datasets Speed Real-World Data Fitness Assessments in Oncology

By Chris Burkhardt

An article published by Desai, et al1 that appeared in the May/June 2021 issue of Values & Outcomes Spotlight defined the promise and challenges associated with using real-world evidence (RWE) that draws on real-world data (RWD) sources for health economics and outcomes research (HEOR).

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10/06/2021

Syapse, Merck Collaborate on Cancer Research Fueled by Real-World Data

By Chris Burkhardt

The drugmaker will use Syapse’s real-world clinical, molecular, treatment, and outcomes data on cancer patients to advance research and improve care.

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09/30/2021

Black, low-income patients with cancer at highest risk for severe COVID-19 complications

By Chris Burkhardt

Patients with cancer demonstrated increased risk for severe COVID-19 complications and mortality, according to study results published in Cancer Reports.

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09/30/2021

Black and Low-Income Individuals With Cancer May Be at a Higher Risk for COVID-19 Complications

By Chris Burkhardt

Black and low-income patients with cancer were found to be at a higher risk of having severe complications after being diagnosed with COVID-19, according to findings from a retrospective observational cohort study that was published in Cancer Reports.

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09/29/2021

Real-World Data: How Clear Is Your Picture?

By Antoinette Cummins

When it comes to getting a clear picture from real-world data, breadth of view and careful analysis matter equally.

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04/12/2021

Bringing Real World Evidence into the Care Setting

By Antoinette Cummins

Real-world evidence (RWE) has the potential to be a transformative tool for healthcare providers to enhance the care they deliver to patients.

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02/25/2021

Syapse Looks to Dive Deeper Into Large Health Systems for Data-Driven Cancer Insights

By Antoinette Cummins

(JP) Fresh off a $68 million funding round, Syapse is moving quickly to expand its network of partnerships with life sciences companies, health systems, molecular laboratories, and regulators. “We’re right in the middle of growth mode right now,” CEO Ken Tarkoff said of the 13-year-old company. The San Francisco-based maker of software to support precision oncology care and drug discovery also raised $30 million in a round that closed in May 2020.

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11/17/2020

You Don't Need a Series E to Invest in DEI

By Antoinette Cummins

Companies should invest in diversity early, and that can be done with time and effort rather than money.

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10/29/2020

Merck’s Digital-Health Venture Arm Quickens Investment Pace

By Antoinette Cummins

Drugmaker Merck & Co.’s digital-health venture-capital arm is picking up the pace of its investments and widening its scope even as restrictions imposed by the global coronavirus pandemic have forced it to rethink its operations.

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08/03/2020

FDA, Syapse real-world study reveal higher risk of hospitalization and death among cancer patients with COVID-19, underscore health disparities

By Antoinette Cummins

The FDA’s Oncology Center of Excellence and Syapse presented data at the American Association of Clinical Research COVID-19 and Cancer meeting on an analysis of more than 212,000 health records of people living with cancer across two major health systems in the Midwestern United States.

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06/23/2020

Hahn testifies on COVID-19 response, says FDA on target to hit user fee goals

By Antoinette Cummins

“We have learned that we need to collect real-world evidence in real-time during an emergency … to inform decisions and how we could change them moving forward, so your support for real-world evidence generation would be incredibly helpful,” Hahn said.

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08/25/2019

The real-world evidence project at the FDA adds Syapse to its list of partners in a push past trial boundaries

By Sevan Isaac

8/15/19 - The Oncology Center of Excellence is teaming up with San Francisco-based Syapse to expand beyond electronic health records — or EHRs — in building a multi-sourced program involving data drawn from EHRs and registries, as well as molecular data from testing labs. …

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08/12/2019

South Korea’s SNUH extends partnership with Syapse to expand access to precision medicine

By Sevan Isaac

8/9/19 - Syapse, a company accelerating precision medicine through insights derived from its global health system network, and Seoul National University Hospital (SNUH) in South Korea announced that they have extended their partnership with a new multi-year agreement. As part of their partnership, SNUH and Syapse will collaboratively work towards b…

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06/08/2019

Syapse, Pfizer enter deal to develop precision medicine in oncology

By Sevan Isaac

7/23/19 - San Francisco-based Syapse said Tuesday that it had signed a collaboration deal with New York-based drugmaker Pfizer that will involve using real-world data from Syapse’s network of community health system providers to understand molecular testing and treatment choices. The partnership marks the company’s third such deal with a major drug…

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05/03/2019

Amgen taps Syapse to infuse real-world data into its cancer clinical trial designs

By Sevan Isaac

5/2/19 - Precision medicine company Syapse has launched a collaboration with its one-time Big Pharma benefactor Amgen, with the goal of mining real-world evidence for insights into cancer drug development. Together, Amgen and Syapse will develop observational research analytics aimed at assessing outcomes in areas of unmet need — starting by i…

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03/06/2018

"Syapse Expands Into Asia With Korean Hospital Deal"

By Nicole Shelby

Seoul National University Cancer Hospital will install the Syapse data-aggregation platform in its 28 centers across Korea, while Megazone, a major Amazon Web Services consulting partner in Asia, will provide IT support, the three entities said today.

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03/06/2018

"Medidata, Syapse partner to enhance oncology clinical trials"

By Nicole Shelby

Syapse, a precision medicine solutions provider and Medidata, a provider of cloud-based technology and data analytics for clinical research, are joining forces.

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03/06/2018

"Syapse, Roche partner to further cancer-focused precision medicine"

By Nicole Shelby

Syapse, an oncology-focused precision medicine company, entered into a multiyear strategic collaboration with Roche.

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03/06/2018

"Syapse raises a $30M Series D round to scale its precision medicine program"

By Nicole Shelby

“Syapse has developed an advanced precision medicine platform that gives providers the tools needed to drive better outcomes in cancer care,” De Vries stated.

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03/06/2018

"Community providers will help drive the future of precision medicine"

By Nicole Shelby

Physicians now have access to entirely new classes of personalized therapies that can engineer a patient’s own immune cells and turn them into treatments unique to them.

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10/31/2017

"Detroit should serve as model for expanding advanced cancer care"

By Bailey Yuro

We want Detroit to be known again for innovation — this time for revolutionizing how cancer care is delivered.

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08/11/2017

"Q&A With Syapse CEO Ken Tarkoff"

By Bailey Yuro

8/11/17 - Our focus is on improving outcomes for cancer patients. We are, at the highest level, doing what we can to improve outcomes.…

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07/27/2017

"Throw out the fax machines: The cancer world needs to modernize molecular test reporting"

By Bailey Yuro

7/27/17 - We now know that precision medicine not only works but can lead to better outcomes and quality of life. These benefits will expand exponentially as more providers adopt precision medicine, as they will have a much larger pool of real-world data to inform their insights.…

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07/25/2017

"We could do more to fight cancer like McCain’s. The government won’t let us."

By Bailey Yuro

7/25/17 - For us to get closer to a treatment for McCain and the thousands of patients that will come after him, physicians and researchers need to be able to easily share data. We need to tear down the wall between the data so that we can radically reduce the lag between insights and treatment.…

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06/27/2017

"Syapse president: Precision medicine is the reality of cancer care"

By Bailey Yuro

6/27/17 - Precision medicine is providing better outcomes and better quality of life for advanced cancer patients today. That is why precision medicine is not only the future of cancer care, but it is also the present reality of cancer care.…

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06/06/2017

"Make no mistake: Cuts to healthcare won’t be superficial "

By Bailey Yuro

6/6/2017 - Precision oncology is at a critical inflection point: it’s gaining wide popularity with hospital systems and their oncologists are rushing to make it part of routine cancer care. Now is when we need to be doubling down on precision medicine, accelerating its spread to as many practitioners and patients as we can.…

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04/24/2017

"Aurora Health Care launches Oncology Precision Medicine program"

By Bailey Yuro

4/24/17 - The clinic will help clinicians provide more care options for patients using new technology not yet available in Wisconsin called Syapse. Syapse is a leading precision medicine software system bringing together previously fragmented clinical, molecular, treatment and outcomes data to support complex clinical decisions.…

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03/16/2017

"Palo Alto startup that fights cancer with software hires CEO"

By Bailey Yuro

3/16/17 - Palo Alto-based precision medicine startup Syapse announced Wednesday that it’s hiring former RelayHealth executive Ken Tarkoff as its new CEO.…

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